HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloro-7-(2-chloroethoxy)-6-methoxyquinazoline → HCID 68550848, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloro-7-(2-chloroethoxy)-6-methoxyquinazoline | HCID 59682907 | — |
| Reactant | 6-chloro-2H-[1,3]dioxolo[4,5-b]pyridin-7-amine | HCID 68548651 | — |
| Product | HCID 68550848 | HCID 68550848 | 92% |
Reaction Steps
Using an analogous procedure to that described in Example 1, 4-chloro-7-(2-chloroethoxy)6-methoxyquinazoline was reacted with 4-amino-5-chloro-2,3-methylenedioxypyridine to give the title compound in 92% yield; NMR Spectrum: (DMSOd6 and CD3CO2D) 4.05 (s, 3H), 4.1 (t, 2H), 4.55 (t, 2H), 6.3 (s, 2H), 7.4 (s, 1H), 7.9 (s, 1H), 8.15 (s, 1H), 8.95 (s, 1H); Mass Spectrum: M+H+ 409 and 411.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07462623B2 |
| Source dataset | uspto-grants-2008_12 |
| ORD ID | ord-053daa8e4c6d4637b4deefda0dac4938 |
| Source note | uspto-grants-2008_12 |