Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2374428Generated: October 29, 2026

6-chloro-2H-[1,3]dioxolo[4,5-b]pyridin-7-amine → HCID 68545021, compound

https://huagongshe.com/reaction/2374428

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-chloro-2H-[1,3]dioxolo[4,5-b]pyridin-7-amineHCID 68548651—
Reactant4-Chloro-7-(3-chloropropoxy)-5-[(tetrahydro-2H-pyran-4-yl)oxy]quinazolineHCID 86605297—
ProductHCID 68545021HCID 6854502178%

Reaction Steps

Using an analogous procedure to that described in Example 1, 4-chloro-7-(3-chloropropoxy)-5-tetrahydropyran-4-yloxyquinazoline was reacted with 4-amino-5-chloro-2,3-methylenedioxypyridine to give the title compound in 78% yield; Mass Spectrum: M+H+ 493 and 495.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07462623B2
Source datasetuspto-grants-2008_12
ORD IDord-cd2f8381d384475fbe30d1250cea0ca2
Source noteuspto-grants-2008_12