HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloro-7-(3-chloropropoxy)quinazoline → HCID 68545232, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloro-7-(3-chloropropoxy)quinazoline | HCID 16221514 | — |
| Reactant | 6-chloro-2H-[1,3]dioxolo[4,5-b]pyridin-7-amine | HCID 68548651 | — |
| Product | HCID 68545232 | HCID 68545232 | 89% |
Reaction Steps
Using an analogous procedure to that described in Example 1, 4-chloro-7-(3-chloropropoxy)quinazoline was reacted with 4-amino-5-chloro-2,3-methylenedioxypyridine to give the title compound in 89% yield; NMR Spectrum: (DMSOd6 and CF3CO2D) 2.25 (m, 2H), 3.8 (t, 2H), 4.35 (t, 2H), 6.25 (s, 2H), 7.35 (s, 1H), 7.6 (d, 1H), 7.9 (s, 1H), 8.7 (d, 1H), 9.0 (s, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07462623B2 |
| Source dataset | uspto-grants-2008_12 |
| ORD ID | ord-4af11563eb124daa9a447614afbcdb62 |
| Source note | uspto-grants-2008_12 |