4-Bromo-3,5-dimethylphenol → 4-(4-Bromo-3,5-dimethylphenoxy)-2-methylbutan-2-ol

HRID 237444Notes

Reaction equation

HRID 237444 reaction equation
[Br:1][C:2]1[C:7]([CH3:8])=[CH:6][C:5]([OH:9])=[CH:4][C:3]=1[CH3:10].CC1C=CC(S(O[CH2:22][CH2:23][C:24]([OH:27])([CH3:26])[CH3:25])(=O)=O)=CC=1>>[Br:1][C:2]1[C:7]([CH3:8])=[CH:6][C:5]([O:9][CH2:22][CH2:23][C:24]([CH3:26])([OH:27])[CH3:25])=[CH:4][C:3]=1[CH3:10]

Participants

3

Reactant 2

HCID 819704-Bromo-3,5-dimethylphenolHCID 140012952-Methyl-4-[(4-methylbenzenesulfonyl)oxy]butan-2-ol

Product 1

HCID 679729214-(4-Bromo-3,5-dimethylphenoxy)-2-methylbutan-2-ol

Procedure

The title compound is prepared from 4-bromo-3,5-dimethylphenol and 3-hydroxy-3-methylbutyl 4-methylbenzenesulfonate following a procedure analogous to that described in Step 3 of Intermediate 2. LC (method 1): tR=1.35 min; Mass spectrum (ESI+): m/z=269 [M+H—H2O]+.

Sources & evidence

ORD record
ord-e4989bf4efff40cca74e691b42b4316a
Source dataset
uspto-grants-2014_02
Patent number
US08642585B2

Reaction notes

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