Acetic Anhydride → HCID 178474370, compound

HRID 2374489Notes

Reaction equation

[NH2:1][C:2]1[C:3]([C:7]2[NH:21][C:10]3=[CH:11][C:12]4[C:13]([CH3:20])([CH3:19])[C:14](=[O:18])[NH:15][C:16]=4[CH:17]=[C:9]3[N:8]=2)=[N:4][NH:5][CH:6]=1.[C:22](OC(=O)C)(=[O:24])[CH3:23]>>[CH3:20][C:13]1([CH3:19])[C:12]2[CH:11]=[C:10]3[NH:21][C:7]([C:3]4[C:2]([NH:1][C:22](=[O:24])[CH3:23])=[CH:6][NH:5][N:4]=4)=[N:8][C:9]3=[CH:17][C:16]=2[NH:15][C:14]1=[O:18]

Participants

Reactant 2

HCID 7918Acetic Anhydride

HCID 178429203HCID 178429203, compound

Product 1

HCID 178474370HCID 178474370, compound

Procedure

N-[3-(7,7-Dimethyl-6-oxo-1,5,6,7-tetrahydro-imidazo[4,5-f]indol-2-yl)-1H-pyrazol-4-yl]-acetamide was prepared using 2-(4-amino-1H-pyrazol-3-yl)-7,7-dimethyl-5,7-dihydro-1H-imidazo[4,5-f]indol-6-one (150 mg, 0.53 mmol) and acetic anhydride. The title compound was obtained as white powder (73 mg).

Workup

customN-[3-(7,7-Dimethyl-6-oxo-1,5,6,7-tetrahydro-imidazo[4,5-f]indol-2-yl)-1H-pyrazol-4-yl]-acetamide was prepared

Sources & evidence

ORD record: ord-e74ba7c60aae4ea381ed13a34ab96b5b
Source dataset: uspto-grants-2008_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07462639B2

Reaction notes

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