Acetaldehyde → HCID 178463363, compound

HRID 2374562Notes

Reaction equation

HRID 2374562 reaction equation
[NH2:1][C:2]1[C:3]([C:7]2[NH:23][C:10]3=[CH:11][C:12]4[C:13]([CH3:22])([CH3:21])[C:14](=[O:20])[N:15]([CH2:18][CH3:19])[C:16]=4[CH:17]=[C:9]3[N:8]=2)=[N:4][NH:5][CH:6]=1.[CH:24](=O)[CH3:25]>>[CH2:18]([N:15]1[C:16]2[CH:17]=[C:9]3[N:8]=[C:7]([C:3]4[C:2]([NH:1][CH2:24][CH3:25])=[CH:6][NH:5][N:4]=4)[NH:23][C:10]3=[CH:11][C:12]=2[C:13]([CH3:22])([CH3:21])[C:14]1=[O:20])[CH3:19]

Participants

3

Reactant 2

HCID 177AcetaldehydeHCID 178462936HCID 178462936, compound

Product 1

HCID 178463363HCID 178463363, compound

Procedure

5-Ethyl-2-(4-ethylamino-1H-pyrazol-3-yl)-7,7-dimethyl-5,7-dihydro-1H-imidazo[4,5-f]indol-6-one was prepared using 2-(4-amino-1H-pyrazol-3-yl)-5-ethyl-7,7-dimethyl-5,7-dihydro-1H-imidazo[4,5-f]indol-6-one (100 mg, 0.32 mmol) and acetaldehyde (30 μl, 0.53 mmol). The title compound was obtained as light grey powder (23 mg).

Workup

  1. custom5-Ethyl-2-(4-ethylamino-1H-pyrazol-3-yl)-7,7-dimethyl-5,7-dihydro-1H-imidazo[4,5-f]indol-6-one was prepared

Sources & evidence

ORD record
ord-e70115bbba8245e683214eb1bf783a69
Source dataset
uspto-grants-2008_12
Patent number
US07462639B2

Reaction notes

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