HCID 24885501, compound → (R)-3-(Carbamoylmethyl)-5-methylhexanoic acid

Participants

Reaction Steps

A flask is equipped with a magnetic stirrer and is charged with 3N HCl (100 ml) and (R)-methyl 3-(carbamoylmethyl)-5-methylhexanoate (20 g). The mixture is stirred for 1-10 hours at a temperature of 20° C. to 25° C., followed by quenching with 47% NaOH to pH 3. The resulting slurry is filtered, washed with water, and dried to obtain a white solid of (R)-3-(carbamoylmethyl)-5-methylhexanoic acid.

Provenance & Evidence