HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzonitrile, 4-bromo- → 4-Cyano-4'-(Trifluoromethyl)biphenyl
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzonitrile, 4-bromo- | HCID 12162 | — |
| Reactant | 4-(Trifluoromethyl)phenylboronic acid | HCID 2734389 | — |
| Reactant | 4'-(Trifluoromethyl)-4-biphenylcarbaldehyde | HCID 2782712 | — |
| Product | 4-Cyano-4'-(Trifluoromethyl)biphenyl | HCID 4368463 | — |
Reaction Steps
Prepared by the method of intermediate D2 using 4-trifluoromethylbenzeneboronic acid and 4-bromobenzonitrile. 1H-NMR (DMSO) δ 7.99-7.94 (6H, m) 7.86 (2H, d); MS(APCI+) found (M+1)=248, C14H8NF3requires 247.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07462620B2 |
| Source dataset | uspto-grants-2008_12 |
| ORD ID | ord-5dfd95fae1624e0091146fb2daeab8ac |
| Source note | uspto-grants-2008_12 |