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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2374996Generated: November 1, 2026

Cyclohexanecarbonyl chloride → HCID 58711957, compound

https://huagongshe.com/reaction/2374996

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclohexanecarbonyl chlorideHCID 75938—
ReactantHCID 58711982HCID 58711982—
Reactant6-(1-aminoethyl)-N-[4-(methyloxy)phenyl]-1,2,4-triazin-3-amineHCID 58711999—
ProductHCID 58711957HCID 58711957—

Reaction Steps

In a similar manner as described for Intermediate 62, using 6-(1-aminoethyl)-N-[4-(methyloxy)phenyl]-1,2,4-triazin-3-amine (Intermediate 47) (100 mg, 0.41 mmol), and cyclohexanecarbonyl chloride (0.065 mL, 0.45 mmol) to afford N-[1-(3-{[4-(methyloxy)phenyl]amino}-1,2,4-triazin-6-yl)ethyl]cyclohexane-carboxamide (90 mg) as a yellow solid. MS m/z 356 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07462614B2
Source datasetuspto-grants-2008_12
ORD IDord-123c65ee7b4c440f96f779b2932a3cd7
Source noteuspto-grants-2008_12