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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2375001Generated: November 3, 2026

Phenylacetyl chloride → HCID 58711998, compound

https://huagongshe.com/reaction/2375001

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenylacetyl chlorideHCID 7679—
ReactantHCID 58711967HCID 58711967—
Reactant6-(1-aminoethyl)-N-[4-(methyloxy)phenyl]-1,2,4-triazin-3-amineHCID 58711999—
ProductHCID 58711998HCID 58711998—

Reaction Steps

In a similar manner as described for Intermediate 59, using 6-(1-aminoethyl)-N-[4-(methyloxy)phenyl]-1,2,4-triazin-3-amine (Intermediate 47) (100 mg, 0.41 mmol), and phenylacetyl chloride (0.059 mL, 0.45 mmol) to afford N-[1-(3-{[4-(methyloxy)phenyl]amino}-1,2,4-triazin-6-yl)ethyl]-2-phenylacetamide (50 mg) as a yellow solid. MS m/z 364 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07462614B2
Source datasetuspto-grants-2008_12
ORD IDord-73fc13287aa34e2e84bfa3202f2202d3
Source noteuspto-grants-2008_12