反应详情

The title compound of Example 59 (210 mg, 0.41 mmol) was treated with 4M HCl in dioxane and allowed to stir tightly capped as a slurry for about 4 hours after which the volatile components were evaporated and diethyl ether was added and evaporated several times. The resulting solids were dissolved in methanol, precipitated with diethyl ether, and collected to afford the title compound (161 mg, 0.36 mmol) as a yellow powder in 87% yield.

1. customcapped as a slurry for about 4 hours after which the volatile components
2. customwere evaporated
3. additiondiethyl ether was added
4. customevaporated several times
5. dissolutionThe resulting solids were dissolved in methanol
6. customprecipitated with diethyl ether
7. customcollected