HCID 14915848, compound → HCID 59732106, compound

HRID 2375172Notes

Reaction equation

HRID 2375172 reaction equation
C1C2NC3C(=CC=CC=3)SC=2C=CC=1C(O)=[O:16].[C:18]([N:21]1[C:27]2[CH:28]=[CH:29][CH:30]=[CH:31][C:26]=2[CH2:25][CH2:24][C:23]2[CH:32]=[CH:33][C:34]([C:36](=[O:38])C)=[CH:35][C:22]1=2)(=[O:20])[CH3:19]>>[C:18]([N:21]1[C:27]2[CH:28]=[CH:29][CH:30]=[CH:31][C:26]=2[CH2:25][CH2:24][C:23]2[CH:32]=[CH:33][C:34]([C:36]([OH:16])=[O:38])=[CH:35][C:22]1=2)(=[O:20])[CH3:19]

Participants

3

Reactant 2

HCID 14915848HCID 14915848, compoundHCID 2271159310H-Phenothiazine-2-carboxylic acid

Product 1

HCID 59732106HCID 59732106, compoundYield 62%

Procedure

The experimental protocol used is the same as that described for the synthesis of intermediate 1.10, using 1-(5-acetyl-10,11-dihydro-5H-dibenzo[b,f]azepin-3-yl)ethanone (J. Chem. Soc. 1973, 859-863) as starting product. A pale yellow solid is obtained with a yield of 62%. Melting point: 189-189.5° C.

Workup

  1. customA pale yellow solid is obtained with a yield of 62%

Sources & evidence

ORD record
ord-f43946deabd84345941c79cb17f72f45
Source dataset
uspto-grants-2008_12
Patent number
US07465721B2

Reaction notes

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