{(S)-6-[(R)-4-bromo-7-fluoro-indan-1-yloxy]-2,3-dihydro-benzofuran-3-yl}-acetic acid methyl ester → ((S)-6-{(R)-7-Fluoro-4-[4-(2-hydroxy-2-methyl-propylcarbamoyl)-2,6-dimethyl-phenyl]indan-1-yloxy}-2,3-dihydro-benzofuran-3-yl)-acetic acid methyl ester

참여 물질

역할	이름	HCID	투입량
반응물	{(S)-6-[(R)-4-bromo-7-fluoro-indan-1-yloxy]-2,3-dihydro-benzofuran-3-yl}-acetic acid methyl ester	HCID 86697103	—
반응물	4-bromo-N-(2-hydroxy-2-methyl-propyl)-3,5-dimethyl-benzamide	HCID 86697188	—
생성물	((S)-6-{(R)-7-Fluoro-4-[4-(2-hydroxy-2-methyl-propylcarbamoyl)-2,6-dimethyl-phenyl]indan-1-yloxy}-2,3-dihydro-benzofuran-3-yl)-acetic acid methyl ester	HCID 86697187	—

반응 단계

The title compound is prepared following a procedure analogous to that described in Step 5 in the preparation of Intermediate 1, starting from 4-bromo-N-(2-hydroxy-2-methyl-propyl)-3,5-dimethyl-benzamide.

출처 및 근거

DOI	10.6084/m9.figshare.5104873.v1
특허 번호	US08642585B2
출처 데이터셋	uspto-grants-2014_02
ORD ID	ord-62f3b4a34b2d4b879b0bca427d828b9a
출처 메모	uspto-grants-2014_02