HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 69311189, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 69310039 | HCID 69310039 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 69311189 | HCID 69311189 | — |
Reaction Steps
The Boc protected tert-butyl 4-({4-[cyano(4-ethyl-1,3-thiazol-2(3H)-ylidene)methyl]pyrimidin-2-yl}amino)piperidine-1-carbamate was treated with a solution of 20% TFA in DCM overnight at rt, affording the title compound as a diTFA salt after evaporation of the solvent (52.5%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07465736B2 |
| Source dataset | uspto-grants-2008_12 |
| ORD ID | ord-2cdeda945a4b4f8a9a5935a7fcff6a9c |
| Source note | uspto-grants-2008_12 |