HRID2375613

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID14012326

4-Amino-8-bromo-N-propylcinnoline-3-carboxamide

C12H13BrN4O

HCID16217660

2-(3,5-Dimethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

C14H21BO4

PRODUCTS

生成物

结构：CCCNC(=O)c1nnc2c(-c3cc(OC)cc(OC)c3)cccc2c1N

HCID23630027

4-Amino-8-(3,5-dimethoxyphenyl)-N-propyl-3-cinnolinecarboxamide

C20H22N4O3

收率 93.9%

PROCEDURE

实验过程

Using method A, 4-amino-8-bromo-N-propyl-cinnoline-3-carboxamide (100 mg, 0.33 mmol) and 2-(3,5-dimethoxyphenyl)-4,4,5,5-tetramethyl-(1,3,2)-dioxaborolane (256 mg, 0.97 mmol) were reacted to afford the title compound (110 mg, 93.9% yield) as an off-white solid.

WORKUP

后处理

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