HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Amino-8-bromo-N-propylcinnoline-3-carboxamide → 4-amino-8-(3,5-dimethoxyphenyl)-N-propyl-cinnoline-3-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Amino-8-bromo-N-propylcinnoline-3-carboxamide | HCID 14012326 | — |
| Reactant | 2-(3,5-Dimethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane | HCID 16217660 | — |
| Product | 4-amino-8-(3,5-dimethoxyphenyl)-N-propyl-cinnoline-3-carboxamide | HCID 23630027 | 93.9% |
Reaction Steps
Using method A, 4-amino-8-bromo-N-propyl-cinnoline-3-carboxamide (100 mg, 0.33 mmol) and 2-(3,5-dimethoxyphenyl)-4,4,5,5-tetramethyl-(1,3,2)-dioxaborolane (256 mg, 0.97 mmol) were reacted to afford the title compound (110 mg, 93.9% yield) as an off-white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07465795B2 |
| Source dataset | uspto-grants-2008_12 |
| ORD ID | ord-19fac1a259184230b9b749a7f1480030 |
| Source note | uspto-grants-2008_12 |