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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 237568Generated: October 31, 2026

(S)-Methyl 2-(6-hydroxy-2,3-dihydrobenzofuran-3-yl)acetate → HCID 86697230, compound

https://huagongshe.com/reaction/237568

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(S)-Methyl 2-(6-hydroxy-2,3-dihydrobenzofuran-3-yl)acetateHCID 53393313—
Reactant{(S)-6-[(R)-4-bromo-7-fluoro-indan-1-yloxy]-2,3-dihydro-benzofuran-3-yl}-acetic acid methyl esterHCID 86697103—
ReactantHCID 86697231HCID 86697231—
ProductHCID 86697230HCID 86697230—

Reaction Steps

The title compound is prepared from (S)-4-(7-fluoro-1-hydroxy-2,3-dihydro-1H-inden-4-yl)-5,6-dihydro-2H-pyran-2-one and (S)-methyl 2-(6-hydroxy-2,3-dihydrobenzofuran-3-yl)acetate following a procedure analogous to that described in Step 3 of Intermediate 1. LC (method 7): tR=1.18 min; Mass spectrum (ESI+): m/z=543 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08642585B2
Source datasetuspto-grants-2014_02
ORD IDord-125d2efc55bf4a568d30a2604712632e
Source noteuspto-grants-2014_02