HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 237569Generated: October 27, 2026
Potassium Carbonate → Dimethyl 5-((3-methyloxetan-3-yl)methoxy)isophthalate
https://huagongshe.com/reaction/237569
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 1,3-Benzenedicarboxylic acid, 5-hydroxy-, 1,3-dimethyl ester | HCID 83065 | — |
| Reactant | (3-Methyloxetan-3-yl)methyl 4-methylbenzenesulfonate | HCID 5461213 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | Dimethyl 5-((3-methyloxetan-3-yl)methoxy)isophthalate | HCID 86697232 | — |
Reaction Steps
A mixture of dimethyl 5-hydroxyisophthalate (500 mg), (3-methyloxetan-3-yl)methyl 4-methylbenzenesulfonate (915 mg), and potassium carbonate (850 mg) in N,N-dimethylformamide (3 mL) is stirred at 50° C. for 5 h. The reaction mixture is diluted with water and the precipitate is filtered off, washed with water, and dried to give the title compound. LC (method 7): tR=0.97 min; Mass spectrum (ESI+): m/z=295 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08642585B2 |
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| Source dataset | uspto-grants-2014_02 |
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| ORD ID | ord-8da586deb3d14c35acc66e49914c77e7 |
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| Source note | uspto-grants-2014_02 |
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