HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 1-Bromo-2-(difluoromethoxy)-4-fluorobenzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Ethyl bromodifluoroacetate | HCID 69585 | — |
| Reactant | 2-Bromo-5-fluorophenol | HCID 2724600 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 1-Bromo-2-(difluoromethoxy)-4-fluorobenzene | HCID 45158711 | — |
Reaction Steps
This compound is obtained in the form of an oil (unpurified) by refluxing a mixture of 2-bromo-5-fluorophenol and ethyl bromodifluoroacetate in acetone overnight in the presence of potassium carbonate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07465811B2 |
| Source dataset | uspto-grants-2008_12 |
| ORD ID | ord-dd8014e211a443e6a4313b3292f729a4 |
| Source note | uspto-grants-2008_12 |