HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Aminobenzothiazole → Benzothiazol-6-yl-(6-iodo-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Aminobenzothiazole | HCID 68288 | — |
| Reactant | 4-Chloro-6-iodo-7H-pyrrolo(2,3-d)pyrimidine | HCID 45789732 | — |
| Reactant | tert-butyl 4-(4-chloro-7H-pyrrolo[2,3-d]pyrimidin-6-yl)-3,6-dihydropyridine-1(2H)-carboxylate | HCID 58709797 | — |
| Product | Benzothiazol-6-yl-(6-iodo-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amine | HCID 58710006 | — |
Reaction Steps
Following the General method for the reaction of amines with tert-butyl 4-(4-chloro-7H-pyrrolo[2,3-d]pyrimidin-6-yl)-3,6-dihydropyridine-1(2H)-carboxylate to generate compounds of Formula I-B-Boc, but using 4-chloro-6-iodo-7H-pyrrolo[2,3-d]pyrimidine and benzothiazol-6-ylamine, one obtained the title compound. MS (ES+): m/z 393.88 (100) [MH+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07465726B2 |
| Source dataset | uspto-grants-2008_12 |
| ORD ID | ord-c6cbfb68679d48ed8c420bdf5fe4d937 |
| Source note | uspto-grants-2008_12 |