HCID 58710084, compound → HCID 20991136, compound

Participants

Reaction Steps

To a solution of benzyl-2,2-dimethyl-3-piperidin-1-ylpropanoate (117.0 mg, 0.42 mmol) in ethanol (5 mL) was slowly added 10% wt Palladium in carbon (50 mg, 0.05 mmol). The reaction mixture was left to stir at rt for 1 h under hydrogen. The mixture was filtered through Celite and concentrated in vacuo, which afforded the title compound as a yellow solid. 1H NMR (400 MHz, CDCl3): δ=1.22 (s, 6H), 1.28-1.39 (bs, 2H), 1.74-1.79 (m, 4H), 2.76 (s, 2H), 2.79-3.08 (bs, 4H).

Provenance & Evidence