HCID 68708010, compound → HCID 68706763, compound

HRID 2376300Notes

Reaction equation

HRID 2376300 reaction equation
C([NH:8][C:9]1[C:17]2[O:16][C:15]([CH3:19])([CH3:18])[CH:14]([C:20]3[CH:25]=[CH:24][C:23]([CH:26]([CH3:28])[CH3:27])=[CH:22][CH:21]=3)[C:13]=2[C:12]([CH3:29])=[C:11]([O:30][CH3:31])[C:10]=1[CH3:32])C1C=CC=CC=1>C(OCC)(=O)C.CCCCCC>[CH:26]([C:23]1[CH:24]=[CH:25][C:20]([CH:14]2[C:13]3[C:12]([CH3:29])=[C:11]([O:30][CH3:31])[C:10]([CH3:32])=[C:9]([NH2:8])[C:17]=3[O:16][C:15]2([CH3:19])[CH3:18])=[CH:21][CH:22]=1)([CH3:28])[CH3:27]

Participants

3

Reactant 1

HCID 68708010HCID 68708010, compound

Product 1

HCID 68706763HCID 68706763, compoundYield 83%

Reagents, catalysts & solvents 1

HCID 21226206Ethyl acetate hexaneSolvent

Procedure

Using N-benzyl-3-(4-isopropylphenyl)-5-methoxy-2,2,4,6-tetramethyl-2,3-dihydro-1-benzofuran-7-amine obtained in Reference Example 95, the title compound was synthesized in the same manner as in Reference Example 30. Yield 83%. Melting point: 111-112° C. (ethyl acetate-hexane).

Workup

  1. customobtained in Reference Example 95

Sources & evidence

ORD record
ord-4ecdd71f1c4b41959e278358b304b746
Source dataset
uspto-grants-2008_12
Patent number
US07465815B2

Reaction notes

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