HCID 68707911, compound → HCID 68707072, compound

HRID 2376385Notes

Reaction equation

HRID 2376385 reaction equation
C([NH:8][C:9]1[C:10]([CH3:27])=[C:11]([CH3:26])[C:12]2[O:16][CH2:15][CH:14]([C:17]3[CH:22]=[CH:21][C:20]([CH3:23])=[CH:19][N:18]=3)[C:13]=2[C:24]=1[CH3:25])C1C=CC=CC=1>C(OCC)(=O)C.CCCCCC>[CH3:25][C:24]1[C:13]2[CH:14]([C:17]3[CH:22]=[CH:21][C:20]([CH3:23])=[CH:19][N:18]=3)[CH2:15][O:16][C:12]=2[C:11]([CH3:26])=[C:10]([CH3:27])[C:9]=1[NH2:8]

Participants

3

Reactant 1

HCID 68707911HCID 68707911, compound

Product 1

HCID 68707072HCID 68707072, compoundYield 85%

Reagents, catalysts & solvents 1

HCID 21226206Ethyl acetate hexaneSolvent

Procedure

Using N-benzyl-4,6,7-trimethyl-3-(5-methylpyridin-2-yl)-2,3-dihydro-1-benzofuran-5-amine obtained in Reference Example 278, the title compound was synthesized in the same manner as in Reference Example 30. Yield 85%. Melting point: 125-127° C. (ethyl acetate-hexane).

Workup

  1. customobtained in Reference Example 278

Sources & evidence

ORD record
ord-6794112c5d0946809bf1cdd1154f150d
Source dataset
uspto-grants-2008_12
Patent number
US07465815B2

Reaction notes

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