HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl acetate hexane → HCID 11303984, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl acetate hexane | HCID 21226206 | — |
| Reactant | HCID 68710233 | HCID 68710233 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | HCID 11303984 | HCID 11303984 | 57% |
Reaction Steps
Using (+)-N-(tert-butyl)-N′-((3R)-7-(hydroxymethyl)-3-(4-isopropylphenyl)-4,6-dimethyl-2,3-dihydro-1-benzofuran-5-yl)urea obtained in Example 49, the title compound was synthesized in the same manner as in Example 45. Yield: 57%. Melting point: 209-210° C. (ethyl acetate-hexane). [α]D20=+53.2° (c=0.47, chloroform).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07465815B2 |
| Source dataset | uspto-grants-2008_12 |
| ORD ID | ord-5141b4d3a3a6457fa57879eb820aed0c |
| Source note | uspto-grants-2008_12 |