Ethyl Acetate → HCID 23114385, compound

HRID 2376444Notes

Reaction equation

HRID 2376444 reaction equation
[C:1]1([C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[CH:6]=[CH:5][C:4]([CH:7]2[C:11]3[C:12]([CH3:19])=[C:13]([NH2:18])[C:14]([CH3:17])=[C:15]([CH3:16])[C:10]=3[O:9][CH2:8]2)=[CH:3][CH:2]=1.C([O:29][CH2:30][CH3:31])(=O)C>>[C:1]1([C:20]2[CH:21]=[CH:22][CH:23]=[CH:24][CH:25]=2)[CH:6]=[CH:5][C:4]([CH:7]2[C:11]3[C:12]([CH3:19])=[C:13]([NH:18][C:30](=[O:29])[CH2:31][C:1]([CH3:20])([CH3:6])[CH3:2])[C:14]([CH3:17])=[C:15]([CH3:16])[C:10]=3[O:9][CH2:8]2)=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 8857Ethyl AcetateHCID 68709661HCID 68709661, compound

Product 1

HCID 23114385HCID 23114385, compoundYield 71%

Procedure

Using 3-(biphenyl-4-yl)-4,6,7-trimethyl-2,3-dihydro-1-benzofuran-5-amine obtained in Reference Example 309, the title compound was synthesized in the same manner as in Example 1. Yield: 71%. Melting point: 218-219° C. (ethyl acetate).

Workup

  1. customobtained in Reference Example 309

Sources & evidence

ORD record
ord-b77a71bb97564fbeac5c88c8a831def3
Source dataset
uspto-grants-2008_12
Patent number
US07465815B2

Reaction notes

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