2-Methoxyethylamine → HCID 23113887, compound

HRID 2376496Notes

Reaction equation

HRID 2376496 reaction equation
ClC(Cl)(Cl)CO[C:5](=[O:28])[NH:6][C:7]1[C:8]([CH3:27])=[C:9]([CH3:26])[C:10]2[O:14][CH2:13][CH:12]([C:15]3[CH:20]=[CH:19][C:18]([CH:21]([CH3:23])[CH3:22])=[CH:17][CH:16]=3)[C:11]=2[C:24]=1[CH3:25].[CH3:31][O:32][CH2:33][CH2:34][NH2:35]>CCCCCC.C(OCC)(=O)C>[CH:21]([C:18]1[CH:19]=[CH:20][C:15]([CH:12]2[C:11]3[C:24]([CH3:25])=[C:7]([NH:6][C:5]([NH:35][CH2:34][CH2:33][O:32][CH3:31])=[O:28])[C:8]([CH3:27])=[C:9]([CH3:26])[C:10]=3[O:14][CH2:13]2)=[CH:16][CH:17]=1)([CH3:23])[CH3:22]

Participants

4

Reactant 2

HCID 80182-MethoxyethylamineHCID 86618058HCID 86618058, compound

Product 1

HCID 23113887HCID 23113887, compoundYield 58%

Reagents, catalysts & solvents 1

HCID 21226206Ethyl acetate hexaneSolvent

Procedure

Using 2,2,2-trichloroethyl(3-(4-isopropylphenyl)-4,6,7-trimethyl-2,3-dihydro-1-benzofuran-5-yl)carbamate obtained in Example 138 and 2-methoxyethylamine, the title compound was synthesized in the same manner as in Example 143. Yield: 58%. Melting point: 172-173° C. (hexane-ethyl acetate).

Sources & evidence

ORD record
ord-b643cdb304104abbb426131eff1bcd4b
Source dataset
uspto-grants-2008_12
Patent number
US07465815B2

Reaction notes

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