Propylamine → HCID 23114368, compound

HRID 2376501Notes

Reaction equation

HRID 2376501 reaction equation
ClC(Cl)(Cl)C[O:4][C:5](=O)[NH:6][C:7]1[C:8]([CH3:27])=[C:9]([CH3:26])[C:10]2[O:14][CH2:13][CH:12]([C:15]3[CH:20]=[CH:19][C:18]([CH:21]([CH3:23])[CH3:22])=[CH:17][CH:16]=3)[C:11]=2[C:24]=1[CH3:25].[CH2:31]([NH2:34])[CH2:32][CH3:33]>CCCCCC.C(OCC)(=O)C>[CH:21]([C:18]1[CH:17]=[CH:16][C:15]([CH:12]2[C:11]3[C:24]([CH3:25])=[C:7]([NH:6][C:5]([NH:34][CH2:31][CH2:32][CH3:33])=[O:4])[C:8]([CH3:27])=[C:9]([CH3:26])[C:10]=3[O:14][CH2:13]2)=[CH:20][CH:19]=1)([CH3:23])[CH3:22]

Participants

4

Reactant 2

HCID 7852PropylamineHCID 86618058HCID 86618058, compound

Product 1

HCID 23114368HCID 23114368, compoundYield 53%

Reagents, catalysts & solvents 1

HCID 21226206Ethyl acetate hexaneSolvent

Procedure

Using 2,2,2-trichloroethyl(3-(4-isopropylphenyl)-4,6,7-trimethyl-2,3-dihydro-1-benzofuran-5-yl)carbamate obtained in Example 138 and 1-propylamine, the title compound was synthesized in the same manner as in Example 143. Yield: 53%. Melting point: 177-178° C. (hexane-ethyl acetate).

Sources & evidence

ORD record
ord-1887a86a85e5427998ba186bdff04761
Source dataset
uspto-grants-2008_12
Patent number
US07465815B2

Reaction notes

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