HCID 86612365, compound → HCID 86612364, compound

HRID 2376546Notes

Reaction equation

HRID 2376546 reaction equation
[Br:1][C:2]1[C:10]2[O:9][C:8]([CH3:12])([CH3:11])[C:7](=[O:13])[C:6]=2[C:5]([CH3:14])=[C:4]([NH:15][C:16](=[O:22])[O:17][C:18]([CH3:21])([CH3:20])[CH3:19])[C:3]=1[CH3:23]>C(OCC)(=O)C.CCCCCC>[Br:1][C:2]1[C:10]2[O:9][C:8]([CH3:12])([CH3:11])[CH:7]([OH:13])[C:6]=2[C:5]([CH3:14])=[C:4]([NH:15][C:16](=[O:22])[O:17][C:18]([CH3:21])([CH3:20])[CH3:19])[C:3]=1[CH3:23]

Participants

3

Reactant 1

HCID 86612365HCID 86612365, compound

Product 1

HCID 86612364HCID 86612364, compoundYield 98%

Reagents, catalysts & solvents 1

HCID 21226206Ethyl acetate hexaneSolvent

Procedure

Using tert-butyl (7-bromo-2,2,4,6-tetramethyl-3-oxo-2,3-dihydro-1-benzofuran-5-yl)carbamate obtained in Reference Example 66, the title compound was synthesized in the same manner as in Example 234. Yield: 98%. Melting point: 187-188° C. (ethyl acetate-hexane).

Workup

  1. customobtained in Reference Example 66

Sources & evidence

ORD record
ord-c296461f2374446a864e2db823465d46
Source dataset
uspto-grants-2008_12
Patent number
US07465815B2

Reaction notes

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