HCID 23113839, compound → HCID 23114211, compound

HRID 2376557Notes

Reaction equation

HRID 2376557 reaction equation
O[C:2]1([C:23]2[S:24][CH:25]=[CH:26][CH:27]=2)[C:6]2[CH:7]=[C:8]([NH:13][C:14](=[O:20])[CH2:15][C:16]([CH3:19])([CH3:18])[CH3:17])[C:9]([CH3:12])=[C:10]([CH3:11])[C:5]=2[O:4][C:3]1([CH3:22])[CH3:21]>C(OCC)(=O)C.CCCCCC>[CH3:21][C:3]1([CH3:22])[CH:2]([C:23]2[S:24][CH:25]=[CH:26][CH:27]=2)[C:6]2[CH:7]=[C:8]([NH:13][C:14](=[O:20])[CH2:15][C:16]([CH3:19])([CH3:18])[CH3:17])[C:9]([CH3:12])=[C:10]([CH3:11])[C:5]=2[O:4]1

Participants

3

Reactant 1

HCID 23113839HCID 23113839, compound

Product 1

HCID 23114211HCID 23114211, compoundYield 65%

Reagents, catalysts & solvents 1

HCID 21226206Ethyl acetate hexaneSolvent

Procedure

Using N-(3-hydroxy-2,2,6,7-tetramethyl-3-(2-thienyl)-2,3-dihydro-1-benzofuran-5-yl)-3,3-dimethylbutanamide obtained in Example 248, the title compound was synthesized in the same manner as in Example 271. Yield: 65%. Melting point: 137-138° C. (ethyl acetate-hexane).

Sources & evidence

ORD record
ord-fc7e19421692471b88dd53993c2c2fbf
Source dataset
uspto-grants-2008_12
Patent number
US07465815B2

Reaction notes

Loading…