2-Furyl(diphenyl)methanol → HCID 68710395, compound

HRID 2376596Notes

Reaction equation

HRID 2376596 reaction equation
Br[C:2]1[C:10]2[O:9][CH2:8][C@H:7]([C:11]3[CH:16]=[CH:15][C:14]([CH:17]([CH3:19])[CH3:18])=[CH:13][CH:12]=3)[C:6]=2[C:5]([CH3:20])=[C:4]([NH:21][C:22](=[O:28])[CH2:23][C:24]([CH3:27])([CH3:26])[CH3:25])[C:3]=1[CH3:29].[O:30]1[CH:34]=[CH:33][CH:32]=[C:31]1C(C1C=CC=CC=1)(C1C=CC=CC=1)O>>[O:30]1[CH:34]=[CH:33][CH:32]=[C:31]1[C:2]1[C:10]2[O:9][CH2:8][C@H:7]([C:11]3[CH:12]=[CH:13][C:14]([CH:17]([CH3:19])[CH3:18])=[CH:15][CH:16]=3)[C:6]=2[C:5]([CH3:20])=[C:4]([NH:21][C:22](=[O:28])[CH2:23][C:24]([CH3:26])([CH3:25])[CH3:27])[C:3]=1[CH3:29]

Participants

3

Reactant 2

HCID 110103742-Furyl(diphenyl)methanolHCID 68707779HCID 68707779, compound

Product 1

HCID 68710395HCID 68710395, compoundYield 6%

Procedure

Using (−)-N-((3R)-7-bromo-3-(4-isopropylphenyl)-4,6-dimethyl-2,3-dihydro-1-benzofuran-5-yl)-3,3-dimethylbutanamide obtained in Example 51 and 2-furyl(diphenyl)methanol, the title compound was obtained in the same manner as in Example 107. Yield: 6%. Melting point: 214-217° C. (ethyl acetate-hexane).

Sources & evidence

ORD record
ord-2b6f6fcd86494b99b15822878f401a0e
Source dataset
uspto-grants-2008_12
Patent number
US07465815B2

Reaction notes

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