Water → HCID 23688043, compound

Participants

Reaction Steps

Sodium hydroxide (1 M, 0.25 ml) is added to a solution of 1-[8-(3-fluoro-phenyl)-[1,7]naphthyridin-6-yl]-piperidine-4-carboxylic acid ethyl ester (96 mg, 0.25 mmol) in THF (1 ml). The solution is stirred at room temperature for 24 hours, then heated to 45° C. for 24 hours. Water and ethyl acetate are added and the aqueous phase separated and evaporated to give the title compound. MS: APCI 352.0 MH+.

Provenance & Evidence