Hydrochloric Acid → HCID 69145081, compound

Participants

Reaction Steps

An ice-cooled solution of [2-(6,7-difluoro-quinoxalin-2-ylamino)-ethyl]-methyl-carbamic acid dimethyl-ethyl ester, D1 (500 mg, 1.48 mmol) in methanol (20 ml) was treated with HCl in dioxane (4M solution, 4 ml). After stirring under argon at room temperature for 4 h the volatiles were removed in vacuo and the residue was triturated with diethyl ether to afford the title compound as a beige powder (100%).

Provenance & Evidence