反应详情

A solution of 6-chloronicotinic acid (10.00 g, 63.5 mmol) in SOCl2 (37 mL) was heated to reflux for 2 h. The SOCl2 was evaporated to dryness, to afford 12.56 g of the desired product (yield: 93%).

1. temperatureto reflux for 2 h
2. customThe SOCl2 was evaporated to dryness