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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2377116Generated: November 1, 2026

4-Methylmorpholine → HCID 15957086, compound

https://huagongshe.com/reaction/2377116

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MethylmorpholineHCID 7972—
Reactant2-Chloro-4,6-dimethoxy-1,3,5-triazineHCID 18450—
ReactantO-Methylhydroxylamine hydrochlorideHCID 521874—
ReactantHCID 59855820HCID 59855820—
ProductHCID 15957086HCID 15957086—

Reaction Steps

The title compound was prepared as in example 116, step 3, using 3-[(2-ethoxyethoxy)methyl]-1-(4-fluorobenzyl)-1H-pyrrolo[2,3-c]pyridine-5-carboxylic acid, 2-chloro-4,6-dimethoxy-1,3,5-triazine, N-methyl morpholine, and O-methyl hydroxylamine hydrochloride. 1H NMR (400 MHz, DMSO-D6) δ ppm 1.07 (t, J=6.95 Hz, 3H) 3.40 (q, J=6.99 Hz, 2H) 3.47-3.51 (m, 2H) 3.53-3.57 (m, 2H) 3.68 (s, 3H) 4.67 (s, 2H) 5.56 (s, 2H) 7.16 (t, J=8.97 Hz, 2H) 7.31-7.40 (m, 2H) 7.83 (s, 1H) 8.26 (s, 1H) 8.84 (s, 1H) 11.73 (s, 1H)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07468375B2
Source datasetuspto-grants-2008_12
ORD IDord-a26cef411cc247cebe1d28b7206a0e3e
Source noteuspto-grants-2008_12