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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 237740Generated: October 30, 2026

Cyanamidnatrium → 5-[4-(Tetrahydropyran-4-yl)-phenoxymethyl]-4,5-dihydro-oxazol-2-ylamine

https://huagongshe.com/reaction/237740

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyanamidnatriumHCID 57375518—
Reactant4-[4-(Oxiran-2-ylmethoxy)phenyl]oxaneHCID 86640231—
Product5-[4-(Tetrahydropyran-4-yl)-phenoxymethyl]-4,5-dihydro-oxazol-2-ylamineHCID 68523890—

Reaction Steps

The title compound was prepared from 4-(4-oxiranylmethoxy-phenyl)-tetrahydropyran and sodium hydrogen cyanamide according to the procedures employed for the preparation of the compound in Step 2 of Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08642603B2
Source datasetuspto-grants-2014_02
ORD IDord-e6c98fc2a36a47f9b90084ce59ec95ca
Source noteuspto-grants-2014_02