反应详情

To 9-(4-benzyloxy-phenyl)-bicyclo[3.3.1]nonane (4.4 g, 14.6 mmol) in MeOH (100 mL) and EtOAc (100 mL) (warmed to 40° C. to facilitate dissolution, then cooled to room temperature) was added 10% Pd/C (0.5 g) under N2. This mixture was stirred under H2 (1 atm) overnight. The reaction mixture was then filtered through celite. The filtrate was concentrated to give the title compound as a solid.(3.1 g).

1. dissolutiondissolution
2. filtrationThe reaction mixture was then filtered through celite
3. concentrationThe filtrate was concentrated