HCID 68527500, compound → HCID 45788691, compound

HRID 237767Notes

Reaction equation

HRID 237767 reaction equation
[C:1]1([C:7]2[N:12]=[CH:11][C:10]([OH:13])=[CH:9][CH:8]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH:2]=1>CO.[Pd]>[CH:1]1([C:7]2[N:12]=[CH:11][C:10]([OH:13])=[CH:9][CH:8]=2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

4

Reactant 1

HCID 68527500HCID 68527500, compound

Product 1

HCID 45788691HCID 45788691, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

To a solution of 6-cyclohex-1-enyl-pyridin-3-ol (2.2 g, 12.6 mmol) in methanol (45 ml) was added 10% Pd/C (0.22 g) under N2. This mixture was stirred under hydrogen (1 atm) for 3 h. The reaction mixture was filtered through celite. The filtrate was concentrated to a solid (2.2 g) to provide the title compound.

Workup

  1. filtrationThe reaction mixture was filtered through celite
  2. concentrationThe filtrate was concentrated to a solid (2.2 g)

Sources & evidence

ORD record
ord-1bec961635104b7bbd9212609fd497ce
Source dataset
uspto-grants-2014_02
Patent number
US08642603B2

Reaction notes

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