HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Ethyl-2-(4-iodo-2-methoxy-pyridin-3-yl)-5-phenyl-imidazol-1-ol → 5-(4-Bromo-phenyl)-2-(4-iodo-2-methoxy-pyridin-3-yl)-imidazol-1-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Ethyl-2-(4-iodo-2-methoxy-pyridin-3-yl)-5-phenyl-imidazol-1-ol | HCID 59857577 | — |
| Reactant | (4-Bromo-phenyl)-oxo-acetaldehyde oxime | HCID 72814957 | — |
| Product | 5-(4-Bromo-phenyl)-2-(4-iodo-2-methoxy-pyridin-3-yl)-imidazol-1-ol | HCID 59857560 | 18% |
Reaction Steps
(4-Bromo-phenyl)-oxo-acetaldehyde oxime (0.242 g, 1.06 mmol) was reacted as described for the synthesis of 4-ethyl-2-(4-iodo-2-methoxy-pyridin-3-yl)-5-phenyl-imidazol-1-ol and gave the title material (0.090 g, 18%). LCMS (+ESI, M+H+) m/z 472, 474.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07470713B2 |
| Source dataset | uspto-grants-2008_12 |
| ORD ID | ord-cac180b68e4f4afda0a19b51b086dfc1 |
| Source note | uspto-grants-2008_12 |