HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Ethyl-2-(4-iodo-2-methoxy-pyridin-3-yl)-5-phenyl-imidazol-1-ol → 2-(4-Iodo-2-methoxy-pyridin-3-yl)-5-(4-morpholin-4-yl-phenyl)-imidazol-1-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Ethyl-2-(4-iodo-2-methoxy-pyridin-3-yl)-5-phenyl-imidazol-1-ol | HCID 59857577 | — |
| Reactant | (4-Morpholin-4-yl-phenyl)-oxo-acetaldehyde oxime | HCID 72579574 | — |
| Product | 2-(4-Iodo-2-methoxy-pyridin-3-yl)-5-(4-morpholin-4-yl-phenyl)-imidazol-1-ol | HCID 59857561 | 22% |
Reaction Steps
(4-Morpholin-4-yl-phenyl)-oxo-acetaldehyde oxime (0.111 g, 0.474 mmol) was reacted as described for the synthesis of 4-ethyl-2-(4-iodo-2-methoxy-pyridin-3-yl)-5-phenyl-imidazol-1-ol and afforded the title material (0.049 g, 22%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07470713B2 |
| Source dataset | uspto-grants-2008_12 |
| ORD ID | ord-7e867d1ee9344ddf92915a3deaa65385 |
| Source note | uspto-grants-2008_12 |