Diethyl cyclopropane-1,1-dicarboxylate → HCID 68955591, compound

Participants

Reaction Steps

The title compound is prepared using the experimental procedure described in Example 147B except cyclopropane-1,1-dicarboxylic acid diethyl ester is used instead of cyclopropane-1,1-dicarboxylic acid dimethyl ester in Example 147A. The intermediate serving as the starting material for Example 147B is therefore 1-[5-hydroxy-3-(4-methoxy-phenyl)-4-phenyl-4,5-dihydro-isoxazol-5-yl]-cyclopropanecarboxylic acid ethyl ester instead of 1-[5-hydroxy-3-(4-methoxy-phenyl)-4-phenyl-4,5-dihydro-isoxazol-5-yl]-cyclopropanecarboxylic acid methyl ester.

Provenance & Evidence