HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphorus pentachloride → 4-Bromo-2-(methoxyimino)-3-oxobutanoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphorus pentachloride | HCID 24819 | — |
| Reactant | 4-Bromo-2-(methoxyimino)-3-oxobutanoic acid | HCID 53651215 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 4-Bromo-2-(methoxyimino)-3-oxobutanoyl chloride | HCID 53426637 | — |
Reaction Steps
To a solution of 30.20 gm (0.154 moles) of 4-bromo-2-methoxyimino-3-oxo-butyric acid in dichloromethane (230 ml) cooled to −10° C. under an atmosphere of nitrogen was added phosphorous pentachloride (28.10 gm; 0.134 moles) in portions and the solution of 4-bromo-2-methoxyimino-3-oxo butyric acid chloride (IV) in dichloromethane thus obtained is kept cooled to −10° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07470786B2 |
| Source dataset | uspto-grants-2008_12 |
| ORD ID | ord-1bca734cb7d44401a91f34cda1f57d68 |
| Source note | uspto-grants-2008_12 |