HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 3-[4-methoxy-3-(naphthalen-2-yl)-5-nitrophenyl]Propionic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 3-(3-Fluoro-4-methoxyphenyl)propionic acid | HCID 3017966 | — |
| Reactant | Methyl 3-[4-methoxy-3-(naphthalen-2-yl)-5-nitrophenyl]propionate | HCID 22558707 | — |
| Product | 3-[4-methoxy-3-(naphthalen-2-yl)-5-nitrophenyl]Propionic Acid | HCID 22559188 | 83.2% |
Reaction Steps
According to the procedure described in the synthesis method of Intermediate 9 provided that the reaction was carried out for 40 minutes, Intermediate 49 (2.45 g) and 2 N aqueous sodium hydroxide (6.7 ml) were reacted and treated to obtain the title compound (Intermediate 60, 1.96 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07470807B2 |
| Source dataset | uspto-grants-2008_12 |
| ORD ID | ord-5b276a86dd30498f946cfe9287c171a8 |
| Source note | uspto-grants-2008_12 |