HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86614983, compound → HCID 86614982, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86614983 | HCID 86614983 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 86614982 | HCID 86614982 | 89.2% |
Reaction Steps
A solution of Intermediate 56 (1.62 g) in a mixture of ethyl acetate (10 ml) and methanol (3 ml) was added with 10% palladium/carbon (29 mg), and stirred at room temperature for 17 hours under hydrogen atmosphere. The reaction mixture was filtered, and the solvent of the filtrate was evaporated under reduced pressure to obtain the title compound (Intermediate 57, 1.19 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07470807B2 |
| Source dataset | uspto-grants-2008_12 |
| ORD ID | ord-cb24740bc17648e0b61ad1134497d146 |
| Source note | uspto-grants-2008_12 |