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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2378549Generated: October 30, 2026

HCID 86614983, compound → HCID 86614982, compound

https://huagongshe.com/reaction/2378549

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 86614983HCID 86614983—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
SolventEthyl AcetateHCID 8857—
ProductHCID 86614982HCID 8661498289.2%

Reaction Steps

A solution of Intermediate 56 (1.62 g) in a mixture of ethyl acetate (10 ml) and methanol (3 ml) was added with 10% palladium/carbon (29 mg), and stirred at room temperature for 17 hours under hydrogen atmosphere. The reaction mixture was filtered, and the solvent of the filtrate was evaporated under reduced pressure to obtain the title compound (Intermediate 57, 1.19 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07470807B2
Source datasetuspto-grants-2008_12
ORD IDord-cb24740bc17648e0b61ad1134497d146
Source noteuspto-grants-2008_12