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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2378550Generated: November 1, 2026

Sodium Hydroxide → HCID 68742074, compound

https://huagongshe.com/reaction/2378550

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
Reactant3-(3-Fluoro-4-methoxyphenyl)propionic acidHCID 3017966—
ReactantHCID 68741546HCID 68741546—
ProductHCID 68742074HCID 68742074109.7%

Reaction Steps

According to the procedure described in the synthesis method of Intermediate 9 provided that the reaction was carried out for 2 hours, Intermediate 58 (146 mg) and 2 N aqueous sodium hydroxide (0.35 ml) were reacted and treated to obtain the title compound (Compound No. T-2, 135 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07470807B2
Source datasetuspto-grants-2008_12
ORD IDord-b4eef3d544c548808ae9cd84744541c2
Source noteuspto-grants-2008_12