Ethyl chloroformate → 4-Phenylsulfanyl-but-2-ynoic acid ethyl ester

HRID 237865Notes

Reaction equation

[CH2:1]([S:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)[C:2]#[CH:3].Cl[C:12]([O:14][CH2:15][CH3:16])=[O:13]>>[CH2:15]([O:14][C:12](=[O:13])[C:3]#[C:2][CH2:1][S:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)[CH3:16]

Participants

Reactant 2

HCID 10928Ethyl chloroformate

HCID 4131667Phenyl propargyl sulfide

Product 1

HCID 685293794-Phenylsulfanyl-but-2-ynoic acid ethyl ester

Procedure

The title compound was prepared from prop-2-ynylsulfanyl-benzene and ethyl chloroformate in accordance with the procedures of G. Cai et al., Tetrahedron, 2006, (5697-5708).

Sources & evidence

ORD record: ord-68705773253f4cab8a46b226b3a070a2
Source dataset: uspto-grants-2014_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08642603B2

Reaction notes

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