HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → HCID 178483384, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | (1H-Indazol-3-yl)-N,N-dimethylmethanamine | HCID 178483331 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 178483384 | HCID 178483384 | 97.2% |
Reaction Steps
3-Dimethylaminomethyl-1H-indazole (25.6 g, 146 mmol) obtained in Step 2 was dissolved in ethyl acetate (350 mL), and the solution was added with methyl iodide (33.3 mL, 535 mmol), followed by stirring at room temperature overnight. The resulting precipitates were collected by filtration to obtain (1H-indazol-3-ylmethyl)trimethylammonium iodide (45.0 g, 97%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07470717B2 |
| Source dataset | uspto-grants-2008_12 |
| ORD ID | ord-9d51dc26137e4f4caa4ab489dba6e440 |
| Source note | uspto-grants-2008_12 |