Formaldehyde → HCID 178463916, compound

HRID 2379018Notes

Reaction equation

HRID 2379018 reaction equation
[CH3:1][C:2]1[CH:7]=[C:6]([C:8]2[C:16]3[N:15]=[N:14][NH:13][C:12]=3[CH:11]=[CH:10][CH:9]=2)[C:5]([OH:17])=[CH:4][CH:3]=1.[CH2:18]([NH:20][CH2:21][CH3:22])[CH3:19].[CH2:23]=O>C(O)CCC>[CH2:18]([N:20]([CH2:23][C:4]1[CH:3]=[C:2]([CH3:1])[CH:7]=[C:6]([C:8]2[C:16]3[N:15]=[N:14][NH:13][C:12]=3[CH:11]=[CH:10][CH:9]=2)[C:5]=1[OH:17])[CH2:21][CH3:22])[CH3:19]

Participants

5

Reactant 3

HCID 712FormaldehydeHCID 8021DiethylamineHCID 178426830HCID 178426830, compound

Product 1

HCID 178463916HCID 178463916, compoundYield 96.8%

Reagents, catalysts & solvents 1

HCID 2631-ButanolSolvent

Procedure

22.5 g of 4-methyl-6-benzotriazolylphenol, 11.0 g of diethylamine and 5.2 g of paraformaldehyde were dissolved in 25 ml of butanol, and heated to a temperature of 95° to 105° C. at which the solution was allowed to undergo reaction under reflux for about 24 hours. After the reaction, the solvent was removed from the reaction product under reduced pressure to obtain 30 g of 2-diethylaminomethyl-4-methyl-6-benzotriazolylphenol (a Mannich base compound).

Workup

  1. temperatureheated to a temperature of 95° to 105° C. at which the solution
  2. customreaction
  3. temperatureunder reflux for about 24 hours
  4. customAfter the reaction
  5. customthe solvent was removed from the reaction product under reduced pressure

Sources & evidence

ORD record
ord-213e090200c34e3d96d738e3e71153c5
Source dataset
uspto-grants-1994_11
Patent number
US05360692

Reaction notes

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