Methanol → HCID 18957859, compound

Participants

Reaction Steps

1,6-dihydro-1-[3-(2-pyridinylcarbonylamino)propyl]-6-oxo-3-pyridinecarboxylic acid methyl ester (0.260 g, 0.83 retool) was hydrolysed in a mixture consisting of methanol (1.0 ml), water (1.0 ml), and 15% aqueous sodium carbonate (2.0 ml) at 60° for 1.5 hours. The solution was filtered and acidified (to pH 5.5 with acetic acid). The precipitated product was recovered by filtration, washed with water, and dried, MP: 180°-182° C.

Provenance & Evidence