Methanol → HCID 18957855, compound

Participants

Reaction Steps

1,6-dihydro-1-[3-(3-pyridinylcarbonylamino)propyl]-6-oxo-3-pyridinecarboxylic acid methyl ester (0.18 g, 0.57 mmol) was hydrolysed in a mixture consisting of methanol (0.7 ml), water (0.7 ml), and 15% aqueous sodium carbonate (0.7 ml) at 60° C. for 1.3 hours. The solution was acidified (to pH 5.5 with acetic acid). The precipitated product was recovered by filtration, washed with water, and dried, MP: 218°-220° C.

Provenance & Evidence