dihydrothiophen-3(2H)-one 1,1-dioxide → HCID 86748225, compound

HRID 2379090Notes

Reaction equation

HRID 2379090 reaction equation
[N:1]([O-:3])=O.[Na+].[O:5]=[C:6]1[CH2:10][CH2:9][S:8](=[O:12])(=[O:11])[CH2:7]1>O.Cl>[OH:3][N:1]=[C:7]1[C:6](=[O:5])[CH2:10][CH2:9][S:8]1(=[O:12])=[O:11]

Participants

5

Reactant 2

HCID 5150067dihydrothiophen-3(2H)-one 1,1-dioxideHCID 23668193Sodium Nitrite

Product 1

HCID 86748225HCID 86748225, compoundYield 61%

Reagents, catalysts & solvents 2

HCID 313Hydrochloric AcidSolventHCID 962WaterSolvent2×

Procedure

A solution of 8.4 g (120 mmol) of sodium nitrite in 25 ml of water is added dropwise at 0° C. to a suspension of 15.5 g (116 mmol) of 3-oxotetrahydrothiophene dioxide (M. A. Smith et al., J. Chem. Soc. (c) 1967, 2171) in 70 ml of water and 10 ml of conc. hydrochloric acid. After 1 hour at 0° C., the product is filtered off with suction, washed with water and dried in vacuo. 11.5 g (61%) of 2-hydroxyimino-3-oxotetrahydrothiophene dioxide, m.p. 148° C., are obtained.

Workup

  1. filtrationthe product is filtered off with suction
  2. washwashed with water
  3. customdried in vacuo

Sources & evidence

ORD record
ord-ac0a2ef38f80479098791a6125a18389
Source dataset
uspto-grants-1994_11
Patent number
US05360812

Reaction notes

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